MonkeyPix Case: Updated June 14, 2022

Monkeypox incidents have not been directly linked to travel to Central or West Africa or have been reported by people returning from trips to Europe and around the world, with suspected cases being investigated. Many countries are evaluating and the situation is changing very fast. In France, transmission of the virus is subject to long-term surveillance through mandatory reporting. In light of the current warnings, public health France is stepping up surveillance of the infection and sending information and warning messages to healthcare professionals.

MonkeyPix case: Update in France

At 2 pm on June 14, 2022, 125 confirmed cases of monkeypox were reported in France: 91 in Ile-de-France, 11 in Occitan, 9 in Overgene-Rh -ne-Alpes, 3 in Normandy, 3 in Hautes-de-France.

As of 2:00 pm on June 13, 2022, of the 111 confirmed cases, 108 have been investigated, one remains unaccounted for and 2 are under investigation.
In all cases investigated, men aged 20 to 63 years (median age: 35 years).

The onset of symptoms is between May 7, 2022 and June 9, 2022 (Figure). Cases are diagnosed within 7 days (within 0 to 17 days) of the onset of symptoms; Therefore, data for the last week is not collected.

Image – Confirmed case of monkeypox, according to the onset of symptoms, France, May-June 2022 (data as of 06/13/2022)

Of the cases investigated, 77% presented genito-anal rash, 76% presented edema, 68% presented fever, 62% presented with lymphadenopathy, 14% presented with odinophagia, and 5% presented with cough. Of the cases investigated, 7 were immunocompromised; No one was killed.

To date, as in other European countries, these incidents have occurred mainly, but not exclusively, among men who have sex with men (MSM), with no direct contact with people returning from the local area. In most cases multiple sexual partners are reported.

In most cases under investigation, it was declared that they could not identify the person who was infected.

Finally, 9 of the cases investigated, secondary cases, were not vaccinated.

Of the cases investigated, 41 have traveled, stayed or worked abroad before their symptoms began, some in different countries: 19 in Spain, 7 in Belgium, 5 in Germany, 1 in Portugal, 1 in Portugal. 1 in the United Kingdom, 1 in the Netherlands, 1 in Denmark, 1 in Luxembourg, 1 in India, 2 in Switzerland, 1 in the United States, 2 in Mali and 1 in Colombia. These trips do not systematically form a source of pollution and the list of countries cited may change as data is collected.

Given what has been observed in Europe on this disease, targeted communication was quickly applied to MSM people. Messages remind you of the method of transmission, the symptoms and what to do about the symptoms They are currently broadcast digitally on the Sexosafe site dedicated to MSM and through social networks. At the same time, posters, flyers and letters of thanks were distributed to the collaborating actors, ARS and SexoSafe team present on the field. Preventive measures will adapt to the evolution of the situation.

In the case of the normal absence of monkeypox in Europe and in the case of a link reported by cases identified as at risk areas, the current European context creates a warning and suggests contamination in Europe. For this reason, in France, long-term monitoring of monkeypox is strengthened through mandatory notification systems and information and warning messages are sent to health professionals.. Exchanges with other European countries, WHO and ECDC continue.

What is Monkeypox?

Monkeypox is an infectious disease caused by an orthopox virus. This zoonotic disease is usually transmitted to humans by wild rats or primates in the forests of Central and West Africa, but human-to-human transmission is also possible, especially in family homes or care settings.

How is it transmitted?

The monkeypox virus can be transmitted by direct contact with a sick person’s skin or mucous membrane lesions, as well as by drops (saliva, sneeze, spit, etc.). Sexual intercourse, with or without penetration, meets these conditions for contamination and increases the risk of exposure to the virus with multiple partners.

Contamination can also occur through contact with the patient’s environment (bed, clothing, dishes, bath linen, etc.). It is therefore important that patients observe isolation throughout the duration of the disease (until the last scabs disappear, usually 3 weeks).

In Central or West Africa, humans can be infected by contact with animals, wild or captive, dead or alive, such as rats or monkeys.

Infection with the monkeypox virus is not known as an STI, but direct contact with the damaged skin during sexual intercourse facilitates infection.

What are the symptoms?

Infection with the monkeypox virus often begins with a fever, which is often accompanied by headaches, body aches, and fatigue. After about 2 days, a blistering rash appears, formed with a liquid-filled blister that dries, scabs form, and then scarring. May cause itching. Vesicles tend to condense in the mouth, palms of the hands and soles of the feet. The mucous membranes of the mouth and genitals are also affected. The lymph nodes are swollen and painful, under the jaw and in the neck.

Incubation of the disease can last from 5 to 21 days. The fever lasts for about 1 to 3 days. The disease often heals spontaneously, 2 to 3 weeks later but sometimes 4 weeks.

Chickenpox is serious?

The disease is more severe in children and immunocompromised people. It can be complicated by superinfection of skin lesions or by respiratory, digestive, ophthalmic or neurological diseases.

At this stage, the cases reported in Europe are mostly mild, and no deaths have been reported.

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