MonkeyPix Case: Updated June 21, 2022

Monkeypox incidents have not been directly linked to travel to Central or West Africa or have been reported by people returning from trips to Europe and around the world, with suspected cases being investigated. Many countries are evaluating and the situation is changing very fast. In France, transmission of the virus is subject to long-term surveillance through mandatory reporting. In light of the current warnings, public health France has stepped up surveillance of the infection and sent information and warning messages to healthcare professionals.

MonkeyPix case: Update in France

As of 2:00 pm on June 21, 2022, 277 confirmed cases of monkeypox have been reported in France: 195 in Ile-de-France, 16 in Occitan, 14 in Overgene-Rh -ne-Alpes, 16 in New Aquitaine, 12 in Hauts-12-de-France, Provence-Alpes. C কোte d’Azur 12, Normandy 6, Center-Val de Loire 1, Borgoigne-Fran -ois-Comte 1, Grand-Estate 1 and Brittany 3. Of these cases, a first female case has been confirmed, whose mode of transmission is under investigation, and the rest are all male.

Of the 248 cases confirmed at 2:00 pm on June 20, 2022, 243 have been investigated, one remains unaccounted for and 4 are under investigation.

By 20:00 on June 20, 2022, all confirmed cases are men between the ages of 19 and 71 (middle age: 34).

The onset of symptoms is between May 7, 2022 and June 15, 2022 (Figure 1). Cases were diagnosed within 7 days (0 to 22 days range) after the onset of symptoms; Therefore, data for the last week is not collected.

Figure 1. Confirmed case of monkeypox (n = 248), according to the onset of symptoms, France, May-June 2022 (data as on 06/20/2022)

Of the cases investigated, 78% presented with a genito-anal rash, 75% with eruption in another part of the body, 70% with fever, and 69% with lymphadenopathy.

Of the cases investigated, 11 were immunocompromised; No one was killed.

To date, as in other European countries, these phenomena have occurred mainly, but not exclusively, among men who have sex with men (MSM), with no direct contact with people returning from the local area. In most cases multiple sexual partners are reported.

In most cases under investigation, it was declared that they could not identify the person who was infected.

Finally, 38 of the cases under investigation were secondary.

Of the cases investigated, 67 traveled, stayed, or worked abroad before their symptoms began, some in different countries: 35 were reported in Spain, eight in Belgium, six in Germany, and four in the United Kingdom. 4 in United, Switzerland, 3 in Portugal, 2 in Netherlands, 2 in Denmark, 2 in Mali, 2 in Greece, 1 in Luxembourg, 1 in India, 1 in USA, 1 in Colombia, 1 in Morocco, 1 in Cyprus and 1 in Serbia. These trips do not systematically form a source of pollution and the list of quoted countries may change as data is collected.

The next update of this report will be on Tuesday, June 28, 2022.

In light of what has been reported in Europe about the disease, targeted communication was quickly applied to MSM people. Messages remind you of the symptoms and what to do about the symptoms They are currently broadcast digitally and in bars and restaurants via an Affinity Display Network. At the same time, posters, flyers and letters of thanks were distributed to the association, ARS and SexoSafe team present on the field.
Finally, the site sexosafe.fr, dedicated to the sexuality of MSM people, offers a summary of knowledge on the subject and preventive measures.

Resistance actions are constantly adapting to the evolution of the situation and the state of knowledge.

In the case of the normal absence of monkeypox in Europe and in the case of a link reported by cases identified as at risk areas, the current European context creates a warning and suggests contamination in Europe. For this reason, in France, long-term surveillance of monkeypox is strengthened through mandatory notification systems and information and alert messages are sent to health professionals. Exchanges with other European countries, WHO and ECDC continue.

What is Monkeypox?

Monkeypox is an infectious disease caused by an orthopox virus. This zoonotic disease is usually transmitted to humans by wild rats or primates in the forests of Central and West Africa, but human-to-human transmission is also possible, especially in family homes or care settings.

How is it transmitted?

The monkeypox virus can be transmitted by direct contact with a sick person’s skin or mucous membrane lesions, as well as by drops (saliva, sneeze, spit, etc.). Sexual intercourse, with or without penetration, meets these conditions for contamination and increases the risk of exposure to the virus with multiple partners.

Contamination can also occur through contact with the patient’s environment (bed, clothing, dishes, bath linen, etc.). It is therefore important that patients observe isolation throughout the duration of the disease (until the last scabs disappear, usually 3 weeks).

In Central or West Africa, humans can also be infected through contact with animals, wild or captive, dead or alive, such as rats or monkeys.

Infection with the monkeypox virus is not known as an STI, but direct contact with damaged skin during sexual intercourse facilitates infection.

What are the symptoms?

Infection with the monkeypox virus can lead to blistering rashes, which are formed by fluid-filled blisters that dry out, crust, and then stain. May cause itching. Vesicles are more concentrated on the face, in the anogenital area, palms of the hands and soles of the feet, but may also be present in the trunk and limbs. The mucous membranes of the mouth and genitals are also affected. These rashes can be accompanied by fever, headache, body aches and athenia. Lymph nodes can be swollen and painful under the jaw, in the neck or in the folds of the groin. Sore throat has also been reported.

Incubation of the disease can last from 5 to 21 days. The fever lasts for about 1 to 3 days. The disease often heals spontaneously, 2 to 3 weeks later but sometimes 4 weeks.

Chickenpox is serious?

The disease is more severe in children and immunocompromised people. It can be complicated by superinfection of skin lesions or by respiratory, digestive, ophthalmic or neurological diseases.

At this stage, the cases reported in Europe are mostly mild, and no deaths have been reported.

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