Covid Long: What if a “virus reservoir” remains in patients’ intestines?

The mystery of it Permanent symptoms of Covid-19 Tends to be brighter. And the theory of a “virus reservoir”, present in the intestines of patients Seems clear.

Directed by PR David R. Walt, Researchers at Harvard Medical School say they have detected the presence of a BBlood IoMarker, Spike Protein65% of so-called “long covid” patients are in the blood. And this, up to 12 months after their first diagnosis.

According to a preliminary survey, it was unveiled on June 16, 2022 in a pre-publication in the Medical Journal. medrRxivThis protein was found in patients without endless symptoms.

The study was reportedly launched after other scientists at Harvard Medical School Detected Presence of viral RNA and spikes in the feces of previously contaminated childrenIGastrointestinal disorders are one of the most frequently reported symptoms by chronic covid patients.

Spike protein has been detected in 65% of patients with long covid

For the purpose of this study, 67 people infected with Covid-19 were selected and their blood plasma samples were taken. Of those, 37, so 30 women said they were suffering from persistent symptoms, “according to other studies that have shown that women are more affected by persistent symptoms.”Research says.

At twelve months, the blood of Covid long patients has been collected “at least twice”. This allows researchers to discover the endless presence of proteins, missing in those who do not suffer from chronic symptoms.

Three Covid-19 antigens, such as “spike protein, S1 subunit and N nucleocapsid, have been found in the plasma of about 75% of patients with symptoms up to 12 months. Infection “Research says.

Spike protein, which allows the virus to enter our cells, was still present in 65% of long-covid patients, whereas it was not present at all in patients who showed no permanent symptoms.

The lifespan of the spike protein in the body is very short, so its presence indicates that there must be some kind of active viral reservoir.“, PR Walt, asked Guardian.

Is asked by Medical News Today Dr. John P., professor of microbiology and immunology at The Weill Cornell Institute of Medicine. Moore believes the protein could be “a surrogate marker for a persistent infection anywhere in the body.”

Viral insistence in the gut?

Such results support the hypothesis, already supported by other studies, A “virus reservoir”, possibly located in the gut, And after a few months of contamination, symptoms like nausea, vomiting or abdominal pain may occur.

Guardian Reveals that Pro Walt and his team also conducted this study in response to a study already published in May 2021 by Harvard Medical School. Subsequently show that the virus RNA has been detected in the stools of children with pediatric multisystem inflammatory syndrome (PIMS).

“Pediatric Multi-Systemic Inflammatory Syndrome (PIMS) is a new systemic inflammatory disease in children that has emerged in the wake of the SARS-CoV-2 infection epidemic. ) Not very specific ”, specified by the higher health authorities.

In April 2022, scientists at Stanford University in California reported that about 13% of people leave viral RNA in their stools even four months after catching covid. An intestinal tissue analysis of 46 people with inflammatory bowel disease showed that RNA or protein could be detected in 70% of patients after seven months, a study published in May 2022 confirmed.

The question is whether the persistence of the virus in the gut or anywhere else in the body can somehow overwhelm the immune system and cause chronic symptoms.Ami Bhatune, a member of the pro-vault team, explained to the British daily.

For his part, the research director “wants to deepen his research to explain why About 35-40% of patients with long covid did not have spike protein in their blood. “” Does this mean that their symptoms came from something other than long covid or does it mean that covid is long versatile? “, He said in amazement at the microphone. Medical News Today.

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